Welcome to the GEDD Focus Group
In the Spotlight:
Check out the GEDD@MSU blog from David Arnosti
New research at cellular level might someday yield big results:
Monique Floer, an MSU assistant professor of biochemistry, is embarking on a study to look at how macrophages, a type of cell that is part of the immune system, can express specific genes for specific functions and why other cells cannot.
Next-generation sequencing: The genome jigsaw:
Titus Brown explains why high throughput gene-sequencing technology often produces frustrating results and what is being done to improve it.
What is Transcription?
Transcription is the process by which the enzyme RNA polymerase makes copies of genes in the form of RNA, allowing the information encoded in the DNA to be "expressed". Transcription is a highly regulated process, representing the initial control of the flow of genetic information.
Transcriptional regulation underlies much of development, physiological responses, and cancer. The mechanisms by which RNA polymerase activity is controlled is a central concern of biological research today.
Transcription is controlled by proximal and distal regulatory sequences in the DNA which recruit transcription factors to a gene. Basal transcription factors are thought to participate in the transcription of most genes, while regulatory factors control transcription in a promoter-specific fashion.
→ Read more about transcription, and who is studying it at Michigan State University.