Zachary Burton Recent Publications
Feig M, Burton ZF. RNA polymerase II flexibility during translocation from normal mode analysis. Proteins. 2009 Aug 5. [Epub ahead of print]
Domecq C, Kireeva M, Archambault J, Kashlev M, Coulombe B, Burton ZF. 2009. Site-directed mutagenesis, purification and assay of Saccharomyces cerevisiae RNA polymerase II. Protein Expr Purif. 69(2010)83–90. Link to article
Thompson NE, Glaser BT, Foley KM, Burton ZF, Burgess RR. 2009. Minimal promoter systems reveal the importance of conserved residues in the B-finger of human transcription factor IIB. J Biol Chem. 284(37):24754-66. Link to article
Kireeva M, Nedialkov YA, Gong XQ, Zhang C, Xiong Y, Moon W, Burton ZF, Kashlev M. (2009) Millisecond phase kinetic analysis of elongation catalyzed by human, yeast, and Escherichia coli RNA polymerase. Methods. Aug;48(4):333-45. Link to article
Kireeva ML, Nedialkov YA, Cremona GH, Purtov YA, Lubkowska L, Malagon F, Burton ZF, Strathern JN, Kashlev M. (2008) Transient reversal of RNA polymerase II active site closing controls fidelity of transcription elongation.Mol Cell. Jun 6;30(5):557-66. Link to reprint
Xiong Y, Burton ZF. (2007) A tunable ratchet driving human RNA polymerase II translocation adjusted by accurately templated nucleoside triphosphates loaded at downstream sites and by elongation factors. J Biol Chem. 14;282(50):36582-92. Link to reprint
Burton ZF, Feig M, Gong XQ, Zhang C, Nedialkov YA, Xiong Y. NTP-driven translocation and regulation of downstream template opening by multi-subunit RNA polymerases. Biochem Cell Biol. 2005 Aug;83(4):486-96. Review. Link to reprint.
Gong, XQ, Zhang, C, Feig, M, and Burton, Z.F. (2005) Dynamic error correction and regulation of downstream bubble opening by human RNA polymerase II. Mol Cell 18:461-470. Link to reprint.
Zhang,C., Zobeck, K.L., and Burton, Z.F.(2005) Human RNA polymerase II elongation in slow motion: role of the TFIIF RAP74 alpha 1 helix in nucleoside triphosphate-driven translocation. Mol Cell Bio 25:3583-3595. Link to reprint.
Ren, D., Nedialkov, Y. A, Li, F., Xu, D, Reimers, S., Finkelstein, A. and Burton, Z. F.(2005) Spacing requirements for simultaneous recognition of the adenovirus major late promoter TATAAAAG box and initiator element Arch Biochem Biophys 435:347-362A. Link to reprint.
Gong, X., Nedialkov, Y., and Burton, Z.F. (2004) Alpha-amanitin blocks translocation by human RNA polymerase II. J. Biol. Chem. 279:27422-27427. Link to reprint
Zhang,C., and Burton, Z.F. (2004) Transcription factors IIF and IIS and nucleoside triphosphate substrates as dynamic probes of the human RNA polymerase II mechanism. J. Mol. Biol. 342:1085-1099. Link to reprint
Zhang, C., Yan, H. and Burton, Z.F. (2003) Combinatorial control of human RNA polymerase II pausing and transcript cleavage by transcription factor IIF, hepatitis delta antigen and TFIIS/SII.J. Biol. Chem. 50:50101-50111. Link to reprint
Nedialkov, Y.A., Gong, X.Q., Hovde, S.L., Yamaguchi, Y., Handa, H., Geiger, J.H., Yan, H. and Burton, Z.F. (2003) NTP-driven translocation by human RNA polymerase II. J. Biol. Chem. 278: 18303-18312. Link to reprint
Nedialkov, Y.A., Gong, X. Q., Yamaguchi, Y., Handa, H. and Burton, Z.F. (2003) Assay of transient state kinetics of elongation by human RNA polymerase II. Methods in Enzymol. 371: 252-264. Link to reprint
Funk, J. D., Nedialkov, Y. A., Xu, Dianpeng and Burton, Z.F. (2002) A key role for the alpha-1 helix of human RAP74 in initiation and elongation of RNA chains. J. Biol. Chem. 277: 46998-47003. Link to reprint
Langelier, M.-F., Forget, D., Rojas, A., Burton, Z.F., and Coulombe, B.(2001) Structural and functional interactions of transcription factor (TF) IIA with TFIIE and TFIIF in transcription initiation by RNA polymerase II. J. Biol. Chem, 276:38652-38657. Link to reprint
Lei, L., Ren, D., and Burton, Z.F. (1999) The RAP74 subunit of human transcription factor IIF has similar roles in initiation and elongation. Mol.Cell.Bio, 19:8372-8382. Link to reprint
Ren, D., Lei, L., and Burton, Z.F. (1999) A region within the RAP74 subunit of human transcription factor IIF is critical for initiation but dispensable for complex assembly. Mol.Cell.Bio 19:7377-7387. Link to reprint
Lei, L., Ren, D., Finkelstein, Ann, and Burton, Z.F.(1998) Functions of the N-and C-terminal domains of human RAP74 in transcriptional initiation, elongation, and recycling of RNA polymerase II. Mol.Cell.Bio.18:2130-2142. Link to reprint
Coulombe, B. and Burton, Z.F. (1999) DNA bending and wrapping around RNA polymerase: A "revolutionary" model describing transcriptional mechanisms. Microbiol. and Molec. Biol. Rev. 53:457-478. Link to reprint
Robert, F., Douziech, M., Forget, D., Egly, J.-M., Greenblatt, J., Burton, Z.F. and Coulombe, B. (1999). Wrapping of promoter DNA around the RNA polymerase II initiation complex induced by TFIIF. Molec. Cell. 2:341-351