Jennifer Ekstrom Recent Publications
Svensson HG, Wedemeyer WJ, Ekstrom JL, Callender DR, Kortemme T, Kim DE, Sjobring U, Baker D. Contributions of amino acid side chains to the kinetics and thermodynamics of the bivalent binding of protein L to Ig kappa light chain. Biochemistry. 2004 Mar 9;43(9):2445-57.
Pauly TA, Ekstrom JL, Beebe DA, Chrunyk B, Cunningham D, Griffor M, Kamath A, Lee SE, Madura R, Mcguire D, Subashi T, Wasilko D, Watts P, Mylari BL, Oates PJ, Adams PD, Rath VL (2003). X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase. Structure. Sep;11(9):1071-8.
Tolbert WD, Zhang Y, Cottet SE, Bennett EM, Ekstrom JL, Pegg AE, Ealick SE (2003). Mechanism of human S-adenosylmethionine decarboxylase proenzyme processing as revealed by the structure of the S68A mutant. Biochemistry. Mar 4;42(8):2386-95.
Bennett EM, Ekstrom JL, Pegg AE, Ealick SE (2002) Monomeric S-adenosylmethionine decarboxylase from plants provides an alternative to putrescine stimulation. Biochemistry. Dec 10;41(49):14509-17.
Ekstrom JL, Pauly TA, Carty MD, Soeller WC, Culp J, Danley DE, Hoover DJ, Treadway JL, Gibbs EM, Fletterick RJ, Day YS, Myszka DG, Rath VL. (2002). Structure-activity analysis of the purine binding site of human liver glycogen phosphorylase. Chem Biol. Aug; 9(8):915-24.
Ekstrom JL, Tolbert WD, Xiong H, Pegg AE, Ealick SE (2001). Structure of a human S-adenosylmethionine decarboxylase self-processing ester intermediate and mechanism of putrescine stimulation of processing as revealed by the H243A mutant. Biochemistry. Aug 14;40(32):9495-504.
Tolbert WD, Ekstrom JL, Mathews II, Secrist JA 3rd, Kapoor P, Pegg AE, Ealick SE (2001). The structural basis for substrate specificity and inhibition of human S-adenosylmethionine decarboxylase. Biochemistry. Aug 14;40(32):9484-94.
Rath VL, Ammirati M, Danley DE, Ekstrom JL, Gibbs EM, Hynes TR, Mathiowetz AM, McPherson RK, Olson TV, Treadway JL, Hoover DJ (2000). Human liver glycogen phosphorylase inhibitors bind at a new allosteric site. Chem Biol. Sep;7(9):677-82.
Ekstrom JL, Mathews II, Stanley BA, Pegg AE, Ealick SE (1999). The crystal structure of human S-adenosylmethionine decarboxylase at 2.25 Å resolution reveals a novel fold. Structure Fold Des. May;7(5):583-95.