Gregg A. Howe Recent Publications

Katsir L, Chung HS, Koo AJK, Howe GA (2008) Jasmonate signaling: a conserved mechanism of hormone sensing. Curr Opin Plant Biol. In press.

Melotto M, Mecey C, Niu Y, Chung HS, Katsir L, Yao J, Zeng W, Staswick P, Browse J, Howe GA, He SY (2008) A critical role of two positively charged amino acids in the Jas motif of Arabidopsis JAZ proteins in mediating coronatine- and jasmonoyl isoleucine-dependent interaction with the COI1 F-box protein Plant J. In press.

Katsir L, Schilmiller AL, Staswick PE, He SY, Howe GA (2008). COI1 is a critical component of a receptor for jasmonate and the bacterial virulence factor coronatine. Proc Natl Acad Sci USA. 105:7100-7105. Link to publication

Chung HS, Koo AJK, Gao X, Jayanty S, Thines B, Jones AD, Howe GA (2008) Regulation and function of Arabidopsis JASMONATE-ZIM domain genes in response to wounding and herbivory. Plant Physiol. 146:952-964. Link to publication

Browse J, Howe GA (2008) Update on jasmonate signaling: New weapons and a rapid response against insect attack. Plant Physiol. 146: 832-383. Link to publication

Howe GA, Jander G. Plant Immunity to Insect Herbivores. Annu Rev Plant Biol. 2007 Nov 21; [Epub ahead of print] Link to publication

Thines B, Katsir L, Melotto M, Niu Y, Mandaokar A, Liu G, Nomura K, He SY, Howe GA, Browse J. 2007. JAZ repressor proteins are targets of the SCF ^CO11 complex during jasmonate signalling. Nature. 448(7154):661-5. Link to publication

Chen H, Gonzales-Vigil E, Wilkerson CG, Howe GA. 2007. Stability of plant defense proteins in the gut of insect herbivores. Plant Physiol. Apr;143(4):1954-67. Abstract

Schilmiller AL, Koo AJ, Howe GA. 2007. Functional diversification of acyl-coenzyme a oxidases in jasmonic acid biosynthesis and action. Plant Physiol. Feb;143(2):812-24. Epub 2006 Dec 15. Abstract

Koo AJ, Chung HS, Kobayashi Y, Howe GA. 2006. Identification of a peroxisomal acyl-activating enzyme involved in the biosynthesis of jasmonic acid in Arabidopsis. J Biol Chem. Nov 3;281(44):33511-20. Epub 2006 Sep 8. Abstract

Powers RA, Rife CL, Schilmiller AL, Howe GA, Garavito RM. 2006. Structure determination and analysis of acyl-CoA oxidase (ACX1) from tomato. Acta Crystallogr D Biol Crystallogr. Jun;62(Pt 6):683-6. Epub 2006 May 12. Abstract

Chen H, Jones AD, Howe GA. 2006. Constitutive activation of the jasmonate signaling pathway enhances the production of secondary metabolites in tomato. FEBS Lett. May 15;580(11):2540-6. Epub 2006 Apr 7. Abstract

Chen H, Wilkerson CG, Kuchar JA, Phinney BS, Howe GA (2005) Jasmonate-inducible plant enzymes degrade essential amino acids in the herbivore midgut. Proc. Natl. Acad. Sci. USA 102:19237-19242.

Li C, Schilmiller AL, Liu G, Lee GI, Jayanty S, Sageman C, Vrebalov J, Giovannoni JJ, Yagi K, Kobayashi Y, Howe GA (2005) Role of b-oxidation in jasmonate biosynthesis and systemic wound signaling in tomato. Plant Cell 17: 971-986.

Schilmiller AL, Howe GA (2005) Systemic signaling in the wound response. Curr Opin Plant Biol 8: 369-377.

Li Li L, Zhao Y, McCaig BC, Wingerd BA, Wang J, Whalon ME, Pichersky E, Howe GA (2004) The tomato homolog of COI1 is required for maternal control of seed maturation, jasmonate-signaled defense responses, and glandular trichome development. Plant Cell 16: 126-143 L, Li C, Lee GI, Howe GA (2002) Distinct roles for jasmonic acid synthesis and action in the systemic wound response of tomato. Proc Natl Acad Sci USA 99: 6416-6421. Supplemental Data

Lee GI, Howe GA (2003) The tomato mutant spr1 is defective in systemin perception and the production of a systemic wound signal for defense gene expression. Plant J 33: 567-576.

Li C, Liu G, Xu C, Lee GI, Bauer P, Ling HQ, Ganal MW, Howe GA (2003) The tomato Suppressor of Prosystemin-mediated Responses2 (Spr2) gene encodes a fatty acid desaturase required for the biosynthesis of jasmonic acid and the production of a systemic wound signal for defense gene expression. Plant Cell 15: 1646-1661.

Zhao Y, Thilmony R, Bender C, Schaller A, He SY, Howe GA (2003) Virulence systems of Pseudomonas syringae pv. tomato promote bacterial speck disease in tomato by targeting the jasmonate signaling pathway. Plant J 36: 485-499. Supplemental Data

Li C, Williams MM, Loh Y-T, Lee GI, Howe GA (2002) Resistance of cultivated tomato to cell content-feeding herbivores is regulated by the octadecanoid-signaling pathway. Plant Physiol 130: 494-503.

Howe GA, Li L, Lee GI, Li C, Shaffer D (2002) Genetic dissection of induced resistance in tomato. In A Schmitt, B Mauch-Mani, eds, Induced Resistance in Plants Against Insects and Diseases. Proceedings of the meeting at Wageningen (The Netherlands), 26-28 April 2002. IOBC/WPRS Bulletin 25(6): 47-52.

Howe GA, Schilmiller AL (2002) Oxylipin metabolism in response to stress. Curr Opin Plant Biol 5: 230-236.

Li L, Li C, Lee GI, Howe GA (2002) Distinct roles for jasmonate synthesis and action in the systemic wound response of tomato. Proc Natl Acad Sci USA 99: 6416-6421.

Strassner J, Schaller F, Frick UB, Howe GA, Weiler EW, Amrhein N, Macheroux P, Schaller A (2002) Characterization and cDNA-microarray expression analysis of 12-oxophytodienoate reductases reveals differential roles for octadecanoid biosynthesis in the local versus the systemic wound response. Plant J 32: 585-601.

Itoh A, Schilmiller AL, McCaig BC, Howe GA (2002) Identification of a jasmonate-regulated allene oxide synthase that metabolizes 9-hydroperoxides of linoleic and linolenic acids. J Biol Chem 277: 46051-46058Howe G, Lightner J, Browse J, Ryan C (1996) An octadecanoid pathway mutant (JL5) of tomato is compromised in signaling for defense against insect attack. Plant Cell 8: 2067-2077.

Froehlich JE, Itoh A, Howe GA (2001) Tomato allene oxide synthase and fatty acid hydroperoxide lyase, two cytochrome P450s involved in oxylipin metabolism, are targeted to different membranes of chloroplast envelope. Plant Physiol 125: 306-317.

Itoh A, Howe GA (2001) Molecular cloning of a divinyl ether synthase: Identification as a CYP74 cytochrome P-450. J Biol Chem 276: 3620-3627.

Li L, Howe GA (2001) Alternative splicing of prosystemin pre-mRNA produces two isoforms that are active as signals in the wound response pathway. Plant Mol Biol 46: 409-419.

Howe GA (2001) Cyclopentenone signals for plant defense: Remodeling the jasmonic acid response. Proc Natl Acad Sci USA 98: 12317-12319.

Li L, Li C, Howe GA (2001) Genetic analysis of wound signaling in tomato: Evidence for a dual role of jasmonic acid in defense and female fertility. Plant Physiol 127: 1414-1417.

Howe GA, Lee GI, Itoh A, Li L, DeRocher A (2000) Cytochrome P450-dependent metabolism of oxylipins in tomato: Cloning and expression of allene oxide synthase and fatty acid hydroperoxide lyase. Plant Physiol 123: 711-724.

Howe GA, Ryan CA (1999) Suppressors of systemin signaling identify genes in the tomato wound response pathway. Genetics 153: 1411-1421.

Howe G, Lightner J, Browse J, Ryan C (1996) An octadecanoid pathway mutant (JL5) of tomato is compromised in signaling for defense against insect attack. Plant Cell 8: 2067-2077.

Howe home page