Laurie S. Kaguni
University Distinguished Professor
- B.A. 1974, University of California, San Diego
- Ph.D. 1980, University of California, Los Angeles
- American Cancer Society, Inc. Postdoctoral Research Fellow, 1980-1983, Stanford University
- American Cancer Society, Inc. Junior Faculty Research Awardee, 1986-1988
- Director, Biochemistry Research Trainee Program, 1998-present
- Distinguished Faculty Award, 2002, 2003; MSU College of Natural Science
- University Distinguished Professor, 2007
- Director, MSU Center for Mitochondrial Science and Medicine, 2008
319 Biochemistry Building
Michigan State University
East Lansing, MI 48824-1319
Office: 517-353-6703
Lab: 517-353-4918
FAX: 517-353-9334
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Laurie S. Kaguni Research Interests continued
Currently under study are the genes encoding the two
subunits of mitochondrial DNA polymerase and that for mtSSB, and the
nuclear proteins that regulate their expression.
Studies of
mitochondrial molecular biology and evolution are crucial to our
understanding of mitochondrial biogenesis and its relationship to cell
growth and its regulation. The recent discovery of mitochondrial DNA
diseases emphasizes the need for future research on the structure and
fidelity of the mitochondrial replication apparatus and on
nuclear-mitochondrial interactions in the regulation of mitochondrial DNA
transactions.
Full text of research interests