John J. LaPres Recent Publications
Lee K, Lynd JD, O'Reilly S, Kiupel M, McCormick JJ, Lapres JJ. (2008) The biphasic role of the hypoxia-inducible factor prolyl-4-hydroxylase, PHD2, in modulating tumor-forming potential. Mol Cancer Res. May;6(5):829-42. Link to article.
Lee K, Roth RA, Lapres JJ. (2007) Hypoxia, drug therapy and toxicity. Pharmacol Ther. Feb;113(2):229-46. Link to article.
Irwin R, Lapres JJ, Kinser S, McCabe LR. (2007) Prolyl-hydroxylase inhibition and HIF activation in osteoblasts promotes an adipocytic phenotype. J Cell Biochem. Feb 15;100(3):762-72. Link to article.
Lee K, Burgoon LD, Lamb L, Dere E, Zacharewski TR, Hogenesch JB, LaPres JJ. (2006) Identification and characterization of genes susceptible to transcriptional cross-talk between the hypoxia and dioxin signaling cascades. Chem Res Toxicol. 2006 Oct;19(10):1284-93. Erratum in: Chem Res Toxicol. Dec;19(12):1702. Link to article.
Vengellur, A., Phillips, J.M., Hogenesch, J.B. and LaPres, J.J. (2005) Gene expression profiling of hypoxia signaling in human hepatocellular carcinoma cells.
Phys. Genomics (22) 308-318. Link to pdf.
Vengellur A, LaPres JJ. (2004) The role of hypoxia inducible factor 1alpha in cobalt chloride induced cell death in mouse embryonic fibroblasts. Toxicol Sci. Dec;82(2):638-46. Epub 2004 Sep 16. Link to pdf.
Vengellur, A., Woods, B., Ryan,, H.E., Johnson, R.S. and LaPres, J.J. (2003) Gene expression profiling of the hypoxia signaling pathway in hypoxia-inducible Factor 1 a null mouse embryonic fibroblasts. Gene Expression(11) 181-197. Link to pdf.
LaPres, J. J., Glover, E., Dunham, E. E., Bunger, M. K., and Bradfield,
C. A. (2000) ARA9 modifies agonist signaling through an increase in available
aryl hydrocarbon receptor. J Biol Chem 275(9), 6153-6159. Link to pdf
Carver L.A., LaPres J.J., Jain S., Dunham, E.E. and Bradfield, C.A.
(1998) Characterization of the Ah Receptor-Associated Protein, ARA9. J
Biol Chem 273, 33580-33587.
La Pres, J.J., and Hudson, L.G., (1996) Identification and
characterization of a determinant of differentiation dependent involucrin
gene expression. J. Biol. Chem. 217, 23154-23160.
Monzon, R.I., La Pres, J.J., and Hudson, L.G., (1996) Retinoic acid and
glucocorticoids transcriptionally regulate involucrin gene expression.
Cell Growth Diff. 7, 1751-1759.