Robert L. Last Recent and Representative Publications

DellaPenna, D and R.L. Last. 2008. Genome-enabled approaches shed new light on plant metabolism. Science. 320:479-481. See PubMed

Schilmiller, A.L., R.L. Last and E. Pichersky. 2008. Harnessing plant trichome biochemistry for the production of useful compounds. Plant J. 54:702-711. See PubMed

Lu Y, Savage LJ, Ajjawi I, Imre KM, Yoder DW, Benning C, Dellapenna D, Ohlrogge JB, Osteryoung KW, Weber AP, Wilkerson CG, Last RL. 2008. New Connections Across Pathways and Cellular Processes: Industrialized Mutant Screening Reveals Novel Associations between Diverse Phenotypes in Arabidopsis. Plant Physiol. Feb 8; [Epub ahead of print] See PubMed

Lee M, Huang T, Toro-Ramos T, Fraga M, Last RL, Jander G. 2008. Reduced activity of Arabidopsis thaliana HMT2, a methionine biosynthetic enzyme, increases seed methionine content. Plant J. Apr;54(2):310-20 See PubMed

Gu L, Jones AD, Last RL. 2007. LC-MS/MS assay for protein amino acids and metabolically related compounds for large-scale screening of metabolic phenotypes. Anal Chem. 79(21):8067-75. Link to article

Kliebenstein, D.J., J.C. D'Auria, A.S. Behere, J.H. Kim, K.L. Gunderson, J.N. Breen, G. Lee, J. Gershenzon, R.L. Last and G. Jander. 2007. Characterization of seed-specific benzoyloxyglucosinolate mutations in Arabidopsis thaliana. Plant J. 51, 1062-1076. Link to pdf

Gu, L., A.D. Jones and R.L. Last. 2007. Rapid LC-MS/MS assay for protein amino acids and metabolically related compounds. Anal. Chem. DOI http://dx.doi.org/10.1021/ac070938b.

Xin, X., A. Mandaokar, J. Chen, R.L. Last and J. Browse. 2007. Arabidopsis ESK1 encodes a novel regulator of freezing tolerance. Plant J.49: 786-799. Link to article

Last, R.L., A.D. Jones and Y. Shachar-Hill. 2007. Towards the Plant Metabolome and Beyond. Nature Rev. Molec. Cell. Biol. 8, 167-174. Link to article

Valentin, H.E., K. Lincoln, F. Moshiri, P.K. Jensen, Q. Qi, T.V. Venkatesh, B. Karunanandaa, S.R. Baszis, S.R. Norris, B. Savidge, K.J. Gruys, R.L. Last. 2006. The Arabidopsis vte5-1 Mutant Reveals a Critical Role for Phytol Kinase in Seed Tocopherol Biosynthesis. Plant Cell. Plant Cell 18: 212-224. Acrobat pdf

Denby, K.J., L.J.M. Jason, S. L. Murray, and R. L. Last. 2005. ups1, an Arabidopsis thaliana camalexin accumulation mutant defective in multiple defence signalling pathways. Plant J. 41:673-84. Acrobat pdf

Jander, G., S.R. Norris, V. Joshi, A. Rugg, M. Fraga, S. Yu, L. Li, and R.L. Last. 2004. Application of a high-throughput HPLC-MS/MS assay to Arabidopsis mutant screening; evidence that threonine aldolase plays a role in seed nutritional quality. Plant J. 39:465-475. Acrobat pdf

Kim, J.H., T.P. Durrett, R.L. Last and G. Jander. 2004. Characterization of the Arabidopsis TU8 glucosinolate mutation, an allele of TERMINAL FLOWER2. Plant Mol. Biol. 54: 671-682. Acrobat pdf

Van Eenennaam, A.L., K. Lincoln, T.P. Durrett, H.E. Valentin, C.K. Shewmaker, G.M. Thorne, J. Jiang, S.R. Baszis , C.K. Levering, E.D. Aasen, M. Hao, J.C. Stein, S.R. Norris, and R.L. Last 2003. Engineering improved vitamin E quality: from Arabidopsis mutant to soy oil. Plant Cell, 15: 3007-3019. Acrobat pdf

Sweetlove, L.J., R.L. Last and A.R. Fernie 2003. Predictive Metabolic Engineering: a Goal for Systems Biology, Plant Physiol., 132: 420-425. Acrobat pdf

Jander, G., S.R. Baerson, J.A. Hudak, K.A. Gonzalez, K.R. Gruys, and R.L. Last. 2003. Saturation mutagenesis in Arabidopsis to determine frequency of herbicide resistance. Plant Physiol., 131: 139-146. Acrobat pdf

Kliebenstein, D.J., J. E. Lim, L.G. Landry, R. L. Last. 2002. The Arabidopsis RCC1 homologue UVR8 mediates UV-B signal transduction and tolerance. Plant Physiol., 130: 234-243. Acrobat pdf

Jander, G, S.R. Norris, S. Rounsley, I. Levin, and R.L. Last. 2002. Arabidopsis map-based cloning in the post-genome era. Plant Physiol., 129: 440-450. Acrobat pdf

Coruzzi, G.M. and R.L. Last. 2000. Amino Acids. In: Biochemistry and Molecular Biology of Plants. R.B. Buchanan, W. Gruissem and R. Jones, eds. Am. Soc. Plant Physiology Press. pp. 358-410.

Conklin, P.L., S.A. Saracco, S.R. Norris, and R.L. Last. 2000. Identification of ascorbic acid-deficient Arabidopsis thaliana mutants. Genetics 154: 847-856. Acrobat pdf

Conklin, P.L., S.R. Norris, G.L. Wheeler, E. H. Williams, N. Smirnoff, and R.L. Last. 1999. Genetic evidence for the role of GDP-mannose in plant ascorbic acid (Vitamin C) biosynthesis. Proc. Natl. Acad. Sci. U.S.A. 96:4198-4203. Acrobat pdf

Zhao, J., C.C. Williams and R.L. Last. 1998. Induction of Arabidopsis tryptophan pathway enzymes and camalexin by amino acid starvation, oxidative stress, and an abiotic elicitor. Plant Cell 10: 359-370. Acrobat pdf

Landry, L.G., A.E. Stapleton, J. Lim, P. Hoffman, J.B. Hays, V. Walbot and R.L. Last. 1997. An Arabidopsis photolyase mutant is hypersensitive to ultraviolet-B radiation. Proc. Natl. Acad. Sci. U.S.A. 94:328-332. Acrobat pdf

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