BRTP Program (Todd Lydic) Genes & Signaling Focus Area (Structural model of human mitochondrial DNA polymerase - L. Kaguni) Structure & Computational Biology Focus Area (Bruker 900 MHz NMR) Plant Biochemistry Focus Area (cDNA Microarray with an Arabidopsis plant and seed - C. Benning)

David G. McConnell
Professor Emeritus
  • A.B. and A.M. 1949, Columbia University
  • Ph.D. 1957, Indiana University
  • Research Associate, 1956-61, Ohio State University
  • Faculty Member, 1962-72, Ohio State University
    Visiting Associate Professor, 1964-66, University of Wisconsin
  • Professor, 1973-2000, Michigan State University

mcconne6@msu.edu
410C Biochemistry Building
Michigan State University
East Lansing, MI 48824-1319
Office: 517-355-2378
Fax: 517-353-9334

Biochemistry 401

Publication search:

David G. McConnell Representative Publications

Binder, A., D. Mc Connell, and N.A. Sjoholm. Verbal conditioning as a function of experimenter characteristics. J. Abnorm. Soc. Psychol. 55, 309 (1957).

McConnell, D. Spontaneous regression and recovery in a sequence of discrimination periods. J. Exp. Psychol. 57, 121 (1959).

McConnell, D. An augmented model for spontaneous regression and recovery. Psychometrika 24, 145 (1959).

Erdman, A.C., A.B. Fontaine, and D.G. McConnell. The amplitude analyzer. Wright Air Defense Command Technical Report 59-45 (1959).

McConnell, D., V.J. Polidora, M.P. Friedman, and D.R. Meyer. Automatic reading and recording of digital data in the analysis of primate behavior. IRE Trans. on Med. Electronics, 121 (1959).

McConnell, D., and M.W. Shelly. Tracking performance on a sequence of step functions which approaches a continuous function as a limit. J. Exp. Psychol. 59, 312 (1960).

Meyer, D.R., V.J. Polidora, and D.G. McConnell. Effects of spatial S-R contiguity and response delay upon discriminative performances by monkeys. J. Comp. Physiol. Psychol. 54, 175 (1961).

Schuck, J.R., V.J. Polidora, D.G. McConnell, and D.R. Meyer. Response location as a factor in primate pattern discrimination. J. Comp. Physiol. Psychol. 54, 543 (1961).

McConnell, D.G., and J.R. Schuck. An analysis of primate responses to colored filmstrip stimuli. J. Comp. Physiol. Psychol. 55, 505 (1962).

Cava, M.P., D.G. McConnell, K. Muth, and M.J. Mitchell. Condensed cyclobutane aromatic compounds. XX. Photolysis of the isomeric 3,3-diphenyldiazoindanones. J. Org. Chem. 27, 1908 (1962).

Craig, E.L., Eglitis, J.A., and D.G. McConnell. Observations on the oil droplets of the principal cone cells of the frog retina. Exp. Eye Res. 2, 268 (1963).

McConnell, D.G. and D.G. Scarpelli. Rhodopsin: an enzyme. Science 13, 848 (1963).

McConnell, D.G. Chemical theories (part of a symposium on excitation of the vertebrate retina). Psychol. Bull. 61, 252 (1964).

McConnell, D.G. Enzymes of the retina. In The Rabbit in Eye Research (Prince, J.H., ed.), C.C. Thomas, Springfield IL, 514-424 (1964).

McConnell, D.G., Wachtel, J. and W.H. Havener. Observations on experimental chloroquine retinopathy. Arch. Ophthalm. 71, 552 (1964).

McConnell, D.G. The isolation of retinal outer segment fragments. J. Cell Biol. 27, 459 (1965).

McConnell, D.G., A. Tzagoloff, D.H. MacLennan, and D.E. Green. Studies on the electron transfer system. LXV. Formation of membranes by purified cytochrome oxidase..J. Biol. Chem. 241, 2373 (1966).

Baum, H., E. Murer, D.B. Slautterback, and D.G. McConnell. Association of integrated metabolic pathways with membranes. II. Electron micrographic studies on glycolytically-active preparations from erythrocytes. Arch. Biochem. Biophys. 113, 487 (1966).

MacLennan, D.H., A. Tzagoloff, and D.G. McConnell. The preparation of microsomal electron transfer complexes. Biochim. Biophys. Acta 131, 59 (1967).

Fleischer, S. and D.G. McConnell. Preliminary observations on the lipids of bovine retinal outer segment discs. Nature 212, 1366 (1967).

Pearse, A.G.E., and D.G. McConnell. Redox compounds in the retinal outer segments. Nature 212, 1368 (1967).

Green, D.E., D.W. Allmann, E. Bachmann, H. Baum, D. Kopaczyk, E.F. Korman, S. Lipton, D.H. MacLennan, D.G. McConnell, J.F. Perdue, J.S. Rieske, and A. Tzagoloff. Formation of membranes by repeating units. Arch. Biochem. Biophys. 119, 312 (1967).

Tzagoloff, A., D.H. MacLennan, D.G. McConnell and D.E. Green. Studies on the electron transfer system. LXVIII. Formation of membranes as the basis of the reconstitution of the mitochondrial electron transfer system. J. Biol. Chem. 242, 2051 (1967).

McConnell, D.G., C.N. Rafferty, and R.A. Dilley. The light-induced proton uptake in bovine retinal outer segment discs. J. Biol. Chem. 243, 5820 (1968).

Brierley, G.P., D. Fleischman, S.D. Hughes, G. Hunter, and D.G. McConnell. Studies on the ion-permeability of the bovine retinal outer segment. I. Preliminary observations. Biochim. Biophys. Acta 163, 117 (1968).

Tzagoloff, A., D.G. McConnell, and D.H. MacLennan. Studies on the electron transfer system. LXIX. Solubilization of the mitochondrial inner membrane by sonic oscillation. J. Biol. Chem. 243, 4117 (1968).

McConnell, D.G., G.W. Ozga, and D.A. Solze. Evidence for glycolysis in bovine retinal microsomes and photoreceptor outer segments. Biochim. Biophys. Acta 184, 11 (1969).

Dilley, R.A., and D.G. McConnell. Alpha-tocopherol in bovine retinal photoreceptor outer segments. J. Membrane Biol. 2, 317 (1970).

Nielsen, N.C., S. Fleischer, and D.G. McConnell. Lipid composition of bovine retinal outer segment fragments. Biochim. Biophys. Acta 211, 10 (1970).

Solze, D.A., and D.G. McConnell. Ultrastructural changes in the rat photoreceptor inner segment during experimental chloroquine retinopathy. Opthalmic Res. 1, 149 (1970).

Manthorpe, C., and D.G. McConnell. Adenylate cyclase in vertebrate retina: relationship to specific fractions and to rhodopsin. J. Biol. Chem. 249, 4608, (1974).

McConnell, D.G. Relationship of the light-induced proton uptake in bovine retinal outer segment fragments to triton-induced membrane disruption and to volume Changes. J. Biol. Chem. 250, 1898 (1975).

Manthorpe, M. and McConnell, D.G. Cyclic nucleotide phosphodiesterases associated with bovine retinal outer segment fragments. Biochim. Biophys. Acta 403, 438 (1975).

McConnell, D.G. If we want GPs, we'll have to admit them to medical school. Urban Health (Oct., 1976).

McConnell, D.G., Baldwin, R.B. and Greenman, P.E. An attitude and background comparison of osteopathic GPs and specialists. The D.O. (Dec., 1976), 103-118.

Rafferty, C.N., J.Y. Cassim, and D.G. McConnell. Circular dichroism, optical rotatory dispersion and absorption studies on the conformation of bovine rhodopsin in situ and solubilized with detergent. Biophys. Struct. Mech. 2, 277 (1977).

McConnell, D.G. and J.B. Melchior. Biochemistry and the osteopathic student. 0st. Annals. 6, l (1978).

McConnell, D.G., M.C. Beal, U. Dinnar, J.P. Goodridge, W.L. Johnston, Z. Karni, J.E. Upledger and G. Blum. Low agreement of findings in neuromusculoskeletal examinations by a group of osteopathic physicians using their own procedures. J. Amer. Osteopathic Assoc. 79, 441 (1980).

Beal, M.C., J.P. Goodridge, W.L. Johnston and D.G. McConnell. Interexaminer agreement on patient improvement after negotiated selection of tests. J. Amer. Osteopathic Assoc. 79, 432 (1980).

Dinnar, U., M.C. Beal, J.P. Goodridge, W.L. Johnston, Z. Karni, F.L. Mitchell, Jr., J.E. Upledger and D.G. McConnell. Classification of diagnostic tests used with osteopathic manipulation. J. Amer. Osteopathic Assoc. 79, 451 (1980).

Young, R.B., D.G. McConnell, C.H. Suelter and T.A. Phillips. Normal and dystrophic embryonic chicken pectoralis muscle cultures. I. Cell differentiation, protein synthesis and enzyme levels. Muscle and Nerve 4, 117 (1981).

McConnell, D.G., R.B. Young and C.H. Suelter. Normal and dystrophic embryonic chicken pectoralis muscle cultures. II.- Ultrastructural comparison. Muscle and Nerve 4, 125 (1981).

McConnell, D.G., M.E. Gardner, A.V. Tuomari, R.B. Young and C.H. Suelter. NormaL and dystrophic embryonic chicken pectoralis muscle cultures. III. Viral infection of normal cell cultures. Muscle and Nerve 4, 131 (1981).

McConnell, D.G., C.A. Dangler, D.M. Eadie, and B.J. Litman. The effect of detergent selection on retinal outer segment A280/A500 ratios. J. Biol. Chem. 256, 4913-4918 (1981).

Kohnken, R.E., Eadie, D.M., Revzin, A. and McConnell, D.G. The light-activated, GTP-dependent cyclic GMP phosphodiesterase complex of bovine retinal rod outer segments: Dark resolution of the catalytic and regulatory proteins. J. Biol. Chem.(1981) 256, 12502-12509.

Kohnken, R.E., Eadie, D.M. and McConnell, D.G. The light-activated, GTP-dependent cyclic GMP phosphodiesterase complex of bovine retinal rod outer segments: reconstitution from catalytic and regulatory proteins in the presence of membranes depleted of soluble proteins. J. Biol. Chem. 256, 12510-12516 (1981).

Kohnken, R.E., Chafouleas, J.G., Eadie, D.M., Means, A.R. and McConnell, D.G. Calmodulin in bovine rod outer segments. J. Biol. Chem. (1981) 256, 12517-12522.

McConnell, D.G., Book Review of Neurochemistry of the Retina, special issue of Neurochem. International, ed. by N. Bazan and R. Lolley, J. Am. Chem. Soc 103:7803-7804 (1981).

Dinnar, U., Beal, M.C., Goodridge, J.P., Johnston, W.L., Karni, Z., Mitchell, F.L., Jr. Upledger, J.E. and McConnell, D.G. Fifty diagnostic tests used with osteopathic manipulation by five physicians in videotaped examination and treatment sessions.J. Amer. Osteopathic Assoc., January 1982, 314/79-321/86.

Beal, M.C., Goodridge, J.P., Johnston, W.L. and McConnell, D.G. Interexaminer agreement on long term patient improvement: An exercise in research design. J. Amer. Osteopathic Medicine, January, 1982, 322/91-328/97.

McConnell, D. G., Kohnken, R. E. and Smith, A. J. Tentative identification of complete amino acid sequence for smallest subunit of GTP-binding protein of bovine retinal rod outer segment. Fed. Proc. 43, 1585 (1984).

Seyfred, M.A., Kohnken, R.E., Collins, C.A. and McConnell, D.G. Rapid diglyceride phosphorylation in isolated bovine rod outer segments. Biochem. Biophys. Res. Comm. 123:121-127 (1984).

Kohnken, R. E. and McConnell, D. G. Use of ?-32P-8-azido-GTP as a probe of the GTP-binding protein subunits in bovine rod outer segments. Biochemistry 24:3803-3809 (1985).

Gehm, B.D. and McConnell, D.G., Phosphoinositide synthesis in bovine rod outer segments. Biochemistry 29:5442-5446 (1990).

Gehm, B.D. and McConnell, D.G., Phosphatidylinositol-4,5-bis-phosphate phospholipase C in bovine rod outer segments. Biochemistry 29:5447-5452 (1990).

Casale, W.L., McConnell, D.G., Wang, S.-Y-, Lee, Y.-J. and Linz, J.E. Expression of a gene family in the dimorphic fungus Mucor racemosus which exhibits striking similarity to human ras genes. Molec. Cell Biol 10:6654-6663 (1990).

Pittler, S.J., Baehr, W., Wasmuth, J.J., McConnell, D.G., Champagne, M.S., Van Tuinen, P., Ledbetter D. and Davis, R.L. Molecular characterization of human and bovinerod photoreceptor cGMP phosphodiesterase a-subunit and chromosomal localization of the human gene. Genomics 6:272-283 (1990).

Gehm, B.D., Pinke, R.M., Laquerre, S., Chafouleas J. G., Schultz, D.A., Pepperl, D.J. and McConnell, D.G. Activation of bovine rod outer segment phosphatidylinositol-4,5-bisphosphate phospholipase C by calmodulin antagonists does not depend on calmodulin. Biochemistry 30:11302-11306 (1991).

Roze, L.V., Mahanti, N., Mehigh, R., McConnell, D.G. and Linz, J.E. Evidence that Mras1 and Mras3 proteins are associated with distinct cellular functions during growth and morphogenesis in the fungus Mucor racemosus. Fungal Genetics and Biology 28, 171-189 (1999).

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