J. Justin McCormick Recent Publications

Lito P, Mets BD, Kleff S, O'Reilly S, Maher VM, McCormick JJ. Evidence That Sprouty 2 Is Necessary for Sarcoma Formation by H-Ras Oncogene-transformed Human Fibroblasts. J Biol Chem. 2008 Jan 25;283(4):2002-9.

Wang Y, Woodgate R, McManus TP, Mead S, McCormick JJ, Maher VM. Evidence that in xeroderma pigmentosum variant cells, which lack DNA polymerase eta, DNA polymerase iota causes the very high frequency and unique spectrum of UV-induced mutations. Cancer Res. 2007 Apr 1;67(7):3018-26.

Lou Z, Maher VM, McCormick JJ. 2005. Identification of the promoter of human transcription factor Sp3 and evidence of the role of factors Sp1 and Sp3 in the expression of Sp3 protein. Gene. 351C:51-59. Epub 2005 Apr 25.

Lou Z, O'Reilly S, Liang H, Maher VM, Sleight SD, McCormick JJ. 2005. Down-regulation of overexpressed sp1 protein in human fibrosarcoma cell lines inhibits tumor formation. Cancer Res. 65(3):1007-17.

Liang H, O'Reilly S, Liu Y, Abounader R, Laterra J, Maher VM, McCormick JJ. 2004. Sp1 regulates expression of MET, and ribozyme-induced down-regulation of MET in fibrosarcoma-derived human cells reduces or eliminates their tumorigenicity. Int J Oncol. 24(5):1057-67.

McCormick JJ, Demos TC, Lomasney LM. 2003. Radiologic case study. Iliopsoas bursitis. Orthopedics. 26(11):1106, 1171-4.

Battle MA, Maher VM, McCormick JJ. 2003. ST7 is a novel low-density lipoprotein receptor-related protein (LRP) with a cytoplasmic tail that interacts with proteins related to signal transduction pathways. Biochemistry. 42(24):7270-82.

H. Liang, R. Abounader, S. O'Reilly, J. Laterra, V.M. Maher, and J.J. McCormick. Inhibition of human fibrosarcoma tumorigenicity by U1 small nuclear RNA/ribozymes targeting expression of hepatocyte growth factor and its receptor MET. Carcinogenesis. (submitted 2002).

X.-D. Wang, Y. Wang, C.W. Lawrence, Y. Murakumo, J.J. McCormick, and V.M. Maher. Expression of exogenous hRev1 in human cells in which UV-or benzo[a]pyrene diol epoxide-induced mutagenesis has been virtually eliminated by antisense hREV1 significantly increases the frequency of mutations. Mol. Cell. Biol. (2002 submitted).

X.-D. Wang, T. P. McManus, J. J. McCormick, and V.M. Maher. Re-expression of wild-type p53 in a focus-derived human fibroblast strain that can produce tumors in athymic mice prevents focus formation, anchorage independence, and tumorigenicity, but does not affect growth in culture. Cancer Res. (2002 submitted).

Z. Li, F. Zhang, T. P. McManus, J. Justin McCormick, C. W. Lawrence, and V.M. Maher. hRev3 is essential for error-prone translesion synthesis past UV or benzo[a]pyrene diol-epoxide-induced DNA lesions in human fibroblasts. Mutation Res.. (2002 submitted).

Z. Li, W. Xiao, J.J. McCormick, and V. M. Maher. Translesion synthesis and damage avoidance contribute almost equally to the tolerance of BPDE adducts in human cells. DNA Repair. (2002 submitted).

Z. Li, W. Xiao, J. J. McCormick and V. M. Maher. 2002. Identification of a protein essential for a major pathway used by human cells to avoid UV-induced DNA damage Proc. Natl. Acad. Sci., USA. 99:4459-4464.

P. A. Havre, S. O'Reilly, J. J. McCormick and D.E., Brash. 2002. Transformed and tumor-derived human cells exhibit preferential sensitivity to the thiol antioxidants, N-acetyl cysteine and penicillamine. Cancer Res. 62, 1443-1449.

S.E. Boley, T.P. McManus, V.M. Maher, and J.J. McCormick. 2000. Malignant transformation of human fibroblast cell strain MSU-1.1 by methylnitrosourea: evidence of homologous recombination to eliminate p53. Cancer Res. 60, 4105-4111.

H. Zhang, G. Marra, B. Tung, J. Jiricny, V.M. Maher and J. J. McCormick. 2000. Postreplicative mismatch repair is required for O6-methylguanine-induced intrachromosomal homologous recombination in human fibroblasts. Carcinogenesis 20, 1639-1646.

S. Huang, V.M. Maher, and J.J. McCormick. 1999. Involvement of intermediary metabolites in the pathway of extracellular Ca2+-induced mitogen activated protein kinase activation in human fibroblasts. Cellular Signalling 11, 263-274.

W.G. McGregor, D. Wei, V.M. Maher, and J.J. McCormick. 1999. Abnormal, error-prone bypass of photoproducts by xeroderma pigmentosum variant cell extracts results in extreme strand bias for the kinds of mutations induced by ultraviolet light. Mol. Cell. Biol. 19, 147-154.

J. Qing, D. Wei, V.M. Maher, and J.J. McCormick. 1999. Cloning and characterization of a novel gene encoding a putative transmembrane protein with altered expression in human tumors. Oncogene 18, 335-342.

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