William L. Smith Representative Publications

Smith, W.L., and D.L. DeWitt. Cyclooxygenase Inhibitors. (2001) In Therapeutic Immunology, (K.F. Austen, S.J. Burakoff, F.S. Rosen, and T.B. Strom, eds.), Blackwell Scientific Publications, Inc., pp. 117-131.

Thuresson, E.D., K.M. Lakkides, C.J. Rieke, Y.Sun, B.Wingerd, R.Micielli, A.M. Mulichak, M.G. Malkowski, R.M.Garavito and W.L. Smith. Prostaglandin endoperoxide H synthase-1: The functions of cyclooxygenase active site residues in the binding, positioning and oxygenation of arachidonic acid. J. Biol. Chem., 276, 1034710357, 2001.

Thuresson, E.D., M.G. Malkowski, K.M. Lakkides, C. J. Rieke, A.M. Mulichak, S. Ginell, R. M. Garavito, and W.L. Smith. Mutational and X-ray crystallographic analysis of the interaction of dihomo-g-linolenic acid with prostaglandin endoperoxide H synthases. J. Biol. Chem., 276, 1035810365, 2001.

Smith, W.L. and R. Langenbach. Why there are two cyclooxygenases. J. Clin. Invest., 107, 14911495, 2001.

Malkowski, M.G., E.D. Thuresson, K.M. Lakkides, C.J. Rieke, R.Micielli, W.L. Smith, and R.M. Garavito. Structure of Eicosapentaenoic and Linoleic Acids in the Cyclooxygenase Site of Prostaglandin Endoperoxide H Synthase-1. J. Biol. Chem., 276, 3754737555, 2001.

Song, I, T. Ball and W.L. Smith. Different suicide inactivation processes for the peroxidase and cyclooxygenase activities of prostaglandin endoperoxide H synthase-1. Biochem. Biophys. Res. Commun., 289, 869-875 (2001).

Dorlet, P., S.A. Siebold, G.T. Babcock, G. J. Gerfen, W.L. Smith, A-L. Tsai and S. Un. High-field EPR study of tyrosyl radicals in prostaglandin H2 synthase-1. Biochemistry, 41, 6107-6114.

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