Gene Regulation and the Function of Transcriptional Repressors
A postdoctoral position is available immediately to study gene regulation and the function of transcriptional repressors using biochemical and transgenic Drosophila techniques. A Ph.D. degree with a strong background in molecular biology or biochemistry is required.
Our department features a strong group of researchers focused on basic mechanisms in transcription, with weekly transcription journal club meetings and supporting coursework. Other departmental focus areas include Structural Biology and Plant Biochemistry. More information about the Department of Biochemistry is available at http://www.bch.msu.edu.
Michigan State University is located in East Lansing, Michigan, adjacent to Lansing, the state capital. The area offers numerous amenities including good public schools, diverse outdoor recreation opportunities, and cultural attractions. More information is available at http://www.msu.edu http://www.ci.east-lansing.mi.us, and http://www.lansing.org.
Send curriculum vitae, a brief description of research experience, and the names of three references to:
David Arnosti, Ph.D
Department of Biochemistry
413 Biochemistry
Michigan State University
East Lansing, MI 48824-1319 USA
Email: arnosti@msu.edu
Immunobiochemistry
The laboratory of Dr. Pam Fraker has a postdoctoral position in immunology available immediately. The lab is beginning studies designed to better understand the adverse impact obesity has on immune defense. Studies will include the morbidly obese undergoing gastric bypass surgery and the obese mouse. Investigation will include a team of MSU faculty and students involved in the nutritional immunology program. Better understanding of the impact of the metabolic and neuroendocrine changes that accompany obesity on host defense systems are also sought. This translational research project requires an industrious candidate willing to combine immunology with metabolism, molecular biology, and neurochemistry.
A generous salary with benefits will be provided. If interested, send a short description of your career goals, CV, and three references to fraker@msu.edu
Studies of type II secretion: the Vibrio cholerae type II pseudopilus.
Laboratory of Dennis N. Arvidson, Ph.D.
A postdoctoral position is available immediately at Michigan State
University, for one year with the possibility of renewal based on
funding availability and performance. The aim of the project is to
employ bacterial genetics, x-ray crystallography, electron microscopy,
biochemical and biophysical studies to develop and validate models for
the base, shaft and tip of the type II pseudopilus. This collaborative
project involves three laboratories at MSU (Arvidson, Wedemeyer and
Bagdasarian) and offers excellent interdisciplinary research
opportunities. The Arvidson laboratory is located in the new Biophysical
and Medical Sciences building. As LS-CAT members we have regular use of
synchrotron beamlines at the APS.
Experience in molecular biology, excellent written and oral
communication skills and the ability to guide junior group members are
required. Experience in protein purification and/or x-ray
crystallography is also desired, but not required.
Applications should include a full CV, publication list, and at least
two names and contact information for references. Send to Dennis
Arvidson at arvidso4@msu.edu. Applications will be reviewed as they are
received and until the position is filled.
Toxicogenomics
Postdoctoral/Research Associate and Graduate Student positions are available to investigate the effect of gestational and lactational exposure to estrogenic chemicals (i.e. estrogenic endocrine disruptors) on testicular gene expression and spermatogenesis in mice. This multidisciplinary project will test the hypothesis that exposure to endocrine disruptors during development compromises male fertility as a result of alterations in testicular gene expression profiles. This position will provide an opportunity to acquire experience in a wide variety of areas including animal handling, sperm assessment, in vitro fertilization, in situ hybridization, cDNA array technology, bioinformatics and the statistical analysis of gene expression data. Further information regarding research activities in the laboratory are available at http://www.bch.msu.edu/~zacharet. This is a multifaceted position that will require a highly motivated and well organized individual with excellent written and oral communication skills. Knowledge of molecular biology and/or biochemistry is essential. Experience with animal handling, statistical analysis, genomics, bioinformatics and database management is highly desirable. Competitive salary, including benefits, will be based on training and experience.
Tim Zacharewski, Ph.D.
Michigan State University
Department of Biochemistry
224 Biochemistry Building
East Lansing, MI 48824-1319 USA
Office Tel: (517) 355-1607
Lab Tel: (517) 353-1944
Fax: (517) 353-9334
E-mail: tzachare@msu.edu